Welcome to the Molecular Enzymology Group pages.

Keywords: enzyme mechanisms, enzyme structure, redox chemistry, biocatalysis, enzyme engineering and exploitation

We are based within the new state-of-the-art research centre, the Manchester Interdisciplinary Biocentre (MIB), we comprise a number of independent but highly complementary research groups who broadly tackle a number of key questions regarding the structures and mechanisms of enzymes. We take a multdisciplinary approach using fast reaction kinetic and spectroscopic methods, X-ray crystallography, NMR, computational chemistry, protein engineering and chemistry to seek a detailed understanding at the atomic level of how enzymes 'work'. With this knowledge enzymes can be developed as drug targets, manipulated for use in biotechnology/biocatalysis or used to further our general understanding of various processes in biology and chemistry. Our work is interdisciplinary and is set at the biomolecular sciences, chemical physics and chemical biology interfaces.